25 YEARS OF SCIENTIFIC DISCOVERY
Our Science
The a2 Milk Company™ are global leaders in beta-casein protein science. For over 25 years, we have worked alongside scientists from around the world to pioneer the scientific understanding of the unique digestive and potential other benefits of A1 protein free milk.
Below you will find key clinical references exploring the digestive effects of A1 and A2-type protein in cows' milk. These human clinical studies contribute to a growing body of evidence suggesting that a2 Milk®, which is sourced from cows that naturally produce milk containing only A2-type protein, and no A1, may be easier on digestion than ordinary milk for some milk intolerant individuals when consumed as part of a healthy varied diet.
Latest Research Findings
Effect of Infant Formula Made With Milk Free of A1-Type β-Casein on Growth and Comfort: A Randomized Controlled Trial
Jing Li, Tingting Yang, and Xiaoyang Sheng
POPULATION: CHINA
Effectiveness of Growing-Up Milk Containing Only A2 β-Casein on Digestive Comfort in Toddlers: A Randomized Controlled Trial in China
Ying Meng, Yubo Zhou, Hongtian Li, Yipu Chen, Grathwohl Dominik, Jie Dong, Youchi Tang, Jose M Saavedra and Jianmeng Liu
POPULATION: CHINA
Comparison of the impact of bovine milk β-casein variants on digestive comfort in females self-reporting dairy intolerance: a randomized controlled trial
Amber M Milan, Aahana Shrestha, Helga J Karlström, Jakob A Martinsson, Nils J Nilsson, Jo K Perry, Li Day, Matthew PG Barnett, and David Cameron-Smith
POPULATION: NEW ZEALAND
Milk Containing A2 β-Casein ONLY, as a Single Meal, Causes Fewer Symptoms of Lactose Intolerance than Milk Containing A1 and A2 β-Caseins in Subjects with Lactose Maldigestion and Intolerance: A Randomized, Double-Blind, Crossover Trial
Monica Ramakrishnan, Tracy K. Eaton, Omer M. Sermet and Dennis A. Savaiano
POPULATION: USA
Effects of milk containing only A2 beta casein versus milk containing both A1 and A2 beta casein proteins on gastrointestinal physiology, symptoms of discomfort, and cognitive behavior of people with self-reported intolerance to traditional cows’ milk
Sun Jianqin, Xu Leiming, Xia Lu, Gregory W. Yelland, Jiayi Ni & Andrew J. Clarke
POPULATION: CHINA
Effects of Conventional Milk Versus Milk Containing Only A2 b-Casein on Digestion in Chinese Children: A Randomized Study
Xiaoyang Sheng, Zailing Li, Jiayi Ni, and Greg Yelland
POPULATION: CHINA
Effects of cow’s milk beta-casein variants on symptoms of milk intolerance in Chinese adults: a multicentre, randomised controlled study
Mei He, Jianqin Sun, Zhuo Qin Jiang, and Yue Xin Yang
POPULATION: CHINA
Note: This is a selection of studies focused on digestive function but is not a comprehensive list of all studies that have been conducted on this subject. Visit betacasein.org for a wider body of evidence including animal trials, in vitro studies and further clinical trials